An inverse-Warburg effect and the origin of Alzheimer’s disease
نویسندگان
چکیده
منابع مشابه
Alzheimer's disease: the amyloid hypothesis and the Inverse Warburg effect
Epidemiological and biochemical studies show that the sporadic forms of Alzheimer's disease (AD) are characterized by the following hallmarks: (a) An exponential increase with age; (b) Selective neuronal vulnerability; (c) Inverse cancer comorbidity. The present article appeals to these hallmarks to evaluate and contrast two competing models of AD: the amyloid hypothesis (a neuron-centric mecha...
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ژورنال
عنوان ژورنال: Biogerontology
سال: 2012
ISSN: 1389-5729,1573-6768
DOI: 10.1007/s10522-012-9403-6